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Recombinant Human Fascin-2 (FSCN2)

ACP21722

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Specifications

Cat.No	ACP21722	Target Name	FSCN2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-492	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O14926

Background Information

Uniprot Id

O14926
Target Species

Human
Target Name

FSCN2
Target Full Name

Fascin-2
Target Function

Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
Target Involvement

Retinitis pigmentosa 30 (RP30)
Target Subcellular Location

Cytoplasm, cytoskeleton. Cell projection, stereocilium.
Target Protein Families

Fascin family
Target Tissue Specificity

Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.
Target Synonyms

Fascin homolog 2; actin bundling protein; retinal Strongylocentrotus purpuratus; Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein; retinal; Fascin-2; FSCN2; FSCN2_HUMAN; Retinal fascin; RFSN; RP30
Target Background

This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.

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Recombinant Human Fascin-2 (FSCN2)

Specifications

Immunogen Information

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