Recombinant Human Feline leukemia virus subgroup C receptor-related protein 1 (FLVCR1), Truncated

Cat.No	ACP05602	Target Name	FLVCR1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP05602

Target Name

FLVCR1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9Y5Y0

Background Information

Uniprot Id

Q9Y5Y0
Target Species

Human
Target Name

FLVCR1
Target Full Name

Choline/ethanolamine transporter FLVCR1
Target Function

Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and is required to maintain intracellular free heme balance, protecting cells from heme toxicity. Heme export provides protection from heme or ferrous iron toxicities in liver, brain, sensory neurons and during erythtopoiesis, a process in which heme synthesis intensifies. Causes susceptibility to FeLV-C in vitro.; Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm. Essential for erythroid differentiation
Target Involvement

Posterior column ataxia with retinitis pigmentosa (PCARP)
Target Subcellular Location

[Isoform 1]: Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Mitochondrion membrane; Multi-pass membrane protein.
Target Protein Families

Major facilitator superfamily, Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family
Target Tissue Specificity

Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.
Target Synonyms

Feline leukemia virus subgroup C cellular receptor; Feline leukemia virus subgroup C receptor; Feline leukemia virus subgroup C receptor related protein 1; Feline leukemia virus subgroup C receptor-related protein 1; FLVC1_HUMAN; FLVCR 1; FLVCR protein; FLVCR1; hFLVCR
Target Background

This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome.

Recombinant Human Feline leukemia virus subgroup C receptor-related protein 1 (FLVCR1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Feline leukemia virus subgroup C receptor-related protein 1 (FLVCR1), Truncated Now

Related Products