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| Cat.No | ACP00442 | Target Name | FARP2 |
|---|---|---|---|
| Target Synonyms | FERM domain-including RhoGEF;FIR;FERM, RhoGEF and pleckstrin domain-containing protein 2;Pleckstrin homology domain-containing family C member 3;PH domain-containing family C member 3 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 44-324aa |
| Mol Weight | 40.3 kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O94887 |
|---|
Uniprot Id
O94887
Target Species
Human
Target Name
FARP2
Target Full Name
FERM, ARHGEF and pleckstrin domain-containing protein 2
Target Function
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
Target Research Area
Neuroscience
Target Synonyms
FARP2; FARP2_HUMAN; FERM; FERM domain including RhoGEF; FERM; RhoGEF and pleckstrin domain protein 2; FERM; RhoGEF and pleckstrin domain-containing protein 2; FGD1 related Cdc42 GEF; FIR; FRG; KIAA0793; PH domain-containing family C member 3; Pleckstrin homology domain-containing family C member 3; PLEKHC3; RhoGEF and pleckstrin domain protein 2; RhoGEF and pleckstrin domain-containing protein 2
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