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| Cat.No | ACP11378 | Target Name | FRMD4A |
|---|---|---|---|
| Target Synonyms | FRMD4A; FRMD4; KIAA1294FERM domain-containing protein 4A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P2Q2 |
|---|
Uniprot Id
Q9P2Q2
Target Species
Human
Target Name
FRMD4A
Target Full Name
FERM domain-containing protein 4A
Target Function
Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4B in epithelial polarization. May regulate MAPT secretion by activating ARF6-signaling.
Target Involvement
Agenesis of the corpus callosum, with facial anomalies and cerebellar ataxia (CCAFCA)
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, tight junction.
Target Synonyms
FRMD4A; FRMD4; KIAA1294FERM domain-containing protein 4A
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