Recombinant Human FGFR1 oncogene partner 2 (FGFR1OP2)

ACP18945

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Specifications

Cat.No	ACP18945	Target Name	FGFR1OP2
Target Synonyms	DKFZp564O1863; FGFR1 oncogene partner 2; FGFR1OP2; FGOP2_HUMAN; Fibroblast growth factor receptor 1 oncogene partner 2; HSPC123; HSPC123 like; WIT3.0; Wound inducible transcript 3.0	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-253
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NVK5

Background Information

Uniprot Id

Q9NVK5
Target Species

Human
Target Name

FGFR1OP2
Target Full Name

FGFR1 oncogene partner 2
Target Function

May be involved in wound healing pathway.
Target Involvement

A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
Target Subcellular Location

Cytoplasm.
Target Protein Families

SIKE family
Target Tissue Specificity

Expressed in bone marrow, spleen and thymus.
Target Synonyms

DKFZp564O1863; FGFR1 oncogene partner 2; FGFR1OP2; FGOP2_HUMAN; Fibroblast growth factor receptor 1 oncogene partner 2; HSPC123; HSPC123 like; WIT3.0; Wound inducible transcript 3.0

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Recombinant Human FGFR1 oncogene partner 2 (FGFR1OP2)

Specifications

Immunogen Information

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