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| Cat.No | ACP17604 | Target Name | FHOD3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2V2M9 |
|---|
Uniprot Id
Q2V2M9
Target Species
Human
Target Name
FHOD3
Target Full Name
FH1/FH2 domain-containing protein 3
Target Function
Actin-organizing protein that may cause stress fiber formation together with cell elongation. Isoform 4 may play a role in actin filament polymerization in cardiomyocytes.
Target Subcellular Location
Cytoplasm, cytoskeleton.; [Isoform 4]: Cytoplasm, myofibril, sarcomere, Z line. Note=Threonine phosphorylation in isoform 4-specific sequence TDTDEEEEVE is required for targeting to myofibrils in cardiomyocytes.
Target Protein Families
Formin homology family
Target Tissue Specificity
Expressed in the heart, kidney and brain. May be down-regulated in various types of heart diseases, including idiopathic dilated, ventricular dilated, familial dilated and perinatal dilated cardiomyopathies, as well as ischemic heart disease (at protein l
Target Synonyms
FLJ22717; Formactin2; FH1/FH2 domain containing protein 3; FH1/FH2 domain-containing protein 3; Fhod3; FHOD3_HUMAN; FHOS2; FLJ22297; Formactin-2; Formin homolog overexpressed in spleen 2; Formin homology 2 domain containing 3; hFHOS2; KIAA1695; mKIAA1695
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