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Recombinant Human Four and a half LIM domains protein 5 (FHL5)

ACP16817

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16817 Target NameFHL5
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-284Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5TD97
Background Information
  • Uniprot Id

    Q5TD97

  • Target Species

    Human

  • Target Name

    FHL5

  • Target Full Name

    Four and a half LIM domains protein 5

  • Target Function

    May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.

  • Target Subcellular Location

    Nucleus. Note=Nuclei of round and elongated spermatids.

  • Target Tissue Specificity

    Testis-specific (at protein level).

  • Target Synonyms

    Activator of cAMP responsive element modulator (CREM) in testis; Activator of cAMP-responsive element modulator in testis; Activator of CREM in testis; FHL-5; Fhl5; FHL5 protein; FHL5_HUMAN; Four and a half LIM domains protein 5

  • Target Background

    The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein.

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