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| Cat.No | ACP01215 | Target Name | GPBAR1 |
|---|---|---|---|
| Target Synonyms | (G-protein coupled receptor GPCR19)(hGPCR19)(Membrane-type receptor for bile acids)(M-BAR)(hBG37)(BG37) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 283-330aa |
| Mol Weight | 20.6 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TDU6 |
|---|
Uniprot Id
Q8TDU6
Target Species
Human
Target Name
GPBAR1
Target Full Name
G-protein coupled bile acid receptor 1
Target Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon
Target Research Area
Others
Target Synonyms
GPBAR1; TGR5; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37
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