Home Products Recombinant Human G-protein coupled receptor 62 (GPR62), Truncated

Recombinant Human G-protein coupled receptor 62 (GPR62), Truncated

ACP07319

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Specifications

Cat.No	ACP07319	Target Name	GPR62
Target Synonyms	GPR62; G-protein coupled receptor 62; G-protein coupled receptor GPCR8; hGPCR8; G-protein coupled receptor KPG_005	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BZJ7

Background Information

Uniprot Id

Q9BZJ7
Target Species

Human
Target Name

GPR62
Target Full Name

G-protein coupled receptor 62
Target Function

Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family
Target Tissue Specificity

Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus.
Target Synonyms

GPR62; G-protein coupled receptor 62; G-protein coupled receptor GPCR8; hGPCR8; G-protein coupled receptor KPG_005
Target Background

Enables arrestin family protein binding activity. Involved in G protein-coupled receptor signaling pathway; inositol phosphate-mediated signaling; and positive regulation of cAMP-mediated signaling. Located in endosome and plasma membrane. Part of receptor complex.

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Recombinant Human G-protein coupled receptor 62 (GPR62), Truncated

Specifications

Immunogen Information

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