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| Cat.No | ACP22197 | Target Name | GALT |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-379 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P07902 |
|---|
Uniprot Id
P07902
Target Species
Human
Target Name
GALT
Target Full Name
Galactose-1-phosphate uridylyltransferase
Target Function
Plays an important role in galactose metabolism.
Target Involvement
Galactosemia (GALCT)
Target Protein Families
Galactose-1-phosphate uridylyltransferase type 1 family
Target Research Area
Metabolism
Target Synonyms
Gal 1 P uridylyltransferase; Gal-1-P uridylyltransferase; Galactose 1 phosphate uridyl transferase; Galactose 1 phosphate uridylyltransferase; Galactose-1-phosphate uridylyltransferase; GALT; GALT_HUMAN; UDP glucose hexose 1 phosphate uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase
Target Background
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.
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