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Recombinant Human Gamma-aminobutyric acid receptor subunit alpha-3 (GABRA3), Truncated

ACP05521

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05521 Target NameGABRA3
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP34903
Background Information
  • Uniprot Id

    P34903

  • Target Species

    Human

  • Target Name

    GABRA3

  • Target Full Name

    Gamma-aminobutyric acid receptor subunit alpha-3

  • Target Function

    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

  • Target Subcellular Location

    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA3 sub-subfamily

  • Target Synonyms

    GABA A Receptor alpha 3; GABA(A) receptor subunit alpha 3; GABA(A) receptor subunit alpha-3; GABR A3; GABRA 3; Gabra3; Gamma aminobutyric acid (GABA) A receptor alpha 3; Gamma aminobutyric acid A receptor alpha 3; Gamma aminobutyric acid receptor subunit alpha 3; Gamma-aminobutyric acid receptor subunit alpha-3; GBRA3_HUMAN; MGC33793

  • Target Background

    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

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