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| Cat.No | ACP05929 | Target Name | GABRG1 |
|---|---|---|---|
| Target Synonyms | GABRG1; Gamma-aminobutyric acid receptor subunit gamma-1; GABA(A) receptor subunit gamma-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N1C3 |
|---|
Uniprot Id
Q8N1C3
Target Species
Human
Target Name
GABRG1
Target Full Name
Gamma-aminobutyric acid receptor subunit gamma-1
Target Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Target Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Target Protein Families
Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRG1 sub-subfamily
Target Synonyms
GABRG1; Gamma-aminobutyric acid receptor subunit gamma-1; GABA(A) receptor subunit gamma-1
Target Background
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4.
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