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| Cat.No | ACP06999 | Target Name | GJA4 |
|---|---|---|---|
| Target Synonyms | GJA4; Gap junction alpha-4 protein; Connexin-37; Cx37 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P35212 |
|---|
Uniprot Id
P35212
Target Species
Human
Target Name
GJA4
Target Full Name
Gap junction alpha-4 protein
Target Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Target Protein Families
Connexin family, Alpha-type (group II) subfamily
Target Tissue Specificity
Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
Target Synonyms
GJA4; Gap junction alpha-4 protein; Connexin-37; Cx37
Target Background
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.
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