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| Cat.No | ACP11134 | Target Name | GMIP |
|---|---|---|---|
| Target Synonyms | ARHGAP46; GEM interacting protein; GEM-interacting protein; GMIP; GMIP_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P107 |
|---|
Uniprot Id
Q9P107
Target Species
Human
Target Name
GMIP
Target Full Name
GEM-interacting protein
Target Function
Stimulates, in vitro and in vivo, the GTPase activity of RhoA.
Target Synonyms
ARHGAP46; GEM interacting protein; GEM-interacting protein; GMIP; GMIP_HUMAN
Target Background
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants.
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