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| Cat.No | ACP00789 | Target Name | SERPINE2 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 20-398aa | Mol Weight | 48.8 kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P07093 |
|---|
Uniprot Id
P07093
Target Species
Human
Target Name
SERPINE2
Target Full Name
Glia-derived nexin
Target Function
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Target Subcellular Location
Secreted, extracellular space.
Target Protein Families
Serpin family
Target Research Area
Cardiovascular
Target Synonyms
GDN; GDN_HUMAN; GDNPF; Glia derived nexin; Glia-derived nexin; Glial derived neurite promoting factor; P17; Peptidase inhibitor 7; Pi-7; Plasminogen activator inhibitor type 1; member 2; PN-1; PN1; PNI; Protease inhibitor 7; Protease nexin 1; Protease nexin I; Serpin E2; Serpin family E member 2; Serpin peptidase inhibitor; clade E (nexin; plasminogen activator inhibitor type 1); member 2; SERPINE 2 ; Serpine2
Target Background
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
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