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| Cat.No | ACP02155 | Target Name | GLP2R |
|---|---|---|---|
| Target Synonyms | GLP-2 receptor;GLP-2-R;GLP-2R | Form | Liquid or Lyophilized powder |
| Expression System | in vitro E.coli expression system | Expression Range | 1-553aa |
| Mol Weight | 64.0 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95838 |
|---|
Uniprot Id
O95838
Target Species
Human
Target Name
GLP2R
Target Full Name
Glucagon-like peptide 2 receptor
Target Function
This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Research Area
Cell Biology
Target Synonyms
GLP2R; Glucagon-like peptide 2 receptor; GLP-2 receptor; GLP-2-R; GLP-2R
Target Background
This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.
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