Recombinant Human Glucose-6-phosphate translocase (SLC37A4), Truncated

Cat.No	ACP05394	Target Name	SLC37A4
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP05394

Target Name

SLC37A4

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	O43826

Background Information

Uniprot Id

O43826
Target Species

Human
Target Name

SLC37A4
Target Full Name

Glucose-6-phosphate exchanger SLC37A4
Target Function

Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels.
Target Involvement

Glycogen storage disease 1B (GSD1B); Glycogen storage disease 1C (GSD1C); Glycogen storage disease 1D (GSD1D)
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

Major facilitator superfamily, Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family
Target Tissue Specificity

Mostly expressed in liver and kidney.
Target Synonyms

G6PT1; G6PT1_HUMAN; G6PT2; G6PT3; Glucose-5-phosphate transporter; Glucose-6-phosphatase; transport (glucose) protein 3; Glucose-6-phosphatase; transport (glucose-6-phosphate) protein 1; Glucose-6-phosphatase; transport (phosphate/pyrophosphate) protein 2,; Glucose-6-phosphate translocase; Glucose-6-phosphate transporter 1; GSD1b; GSD1c; GSD1d; MGC15729; Microsomal glucose-6-phosphate transporter; PRO0685; SLC37A4; Solute carrier family 37 (glucose-6-phosphate transporter); member 4; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19; TRG19
Target Background

This gene regulates glucose-6-phosphate transport from the cytoplasm to the lumen of the endoplasmic reticulum, in order to maintain glucose homeostasis. It also plays a role in ATP-mediated calcium sequestration in the lumen of the endoplasmic reticulum. Mutations in this gene have been associated with various forms of glycogen storage disease. Alternative splicing in this gene results in multiple transcript variants.

Recombinant Human Glucose-6-phosphate translocase (SLC37A4), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Glucose-6-phosphate translocase (SLC37A4), Truncated Now

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