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| Cat.No | ACP05548 | Target Name | GRIK1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P39086 |
|---|
Uniprot Id
P39086
Target Species
Human
Target Name
GRIK1
Target Full Name
Glutamate receptor ionotropic, kainate 1
Target Function
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Target Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family, GRIK1 subfamily
Target Tissue Specificity
Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
Target Synonyms
EAA3; EEA3; Excitatory amino acid receptor 3; GLR5; GluR-5; GluR5; GluR6; GluR7; Glutamate receptor 5; Glutamate receptor; Glutamate receptor ionotropic kainate 1; GRIK1; GRIK1_HUMAN; Human glutamate receptor GLUR5; ionotropic kainate 1; OTTHUMP00000096569
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