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| Cat.No | ACP05726 | Target Name | GPAM |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HCL2 |
|---|
Uniprot Id
Q9HCL2
Target Species
Human
Target Name
GPAM
Target Full Name
Glycerol-3-phosphate acyltransferase 1, mitochondrial
Target Function
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
Target Subcellular Location
Mitochondrion outer membrane; Multi-pass membrane protein.
Target Protein Families
GPAT/DAPAT family
Target Synonyms
Glycerol 3 phosphate acyltransferase 1 mitochondrial; Glycerol 3 phosphate acyltransferase mitochondrial; Glycerol-3-phosphate acyltransferase 1; Gpam; GPAT; GPAT-1; GPAT1; GPAT1_HUMAN; KIAA1560; MGC26846; mitochondrial; RP11-426E5.2
Target Background
This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene.
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