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| Cat.No | ACP14026 | Target Name | GPHA2 |
|---|---|---|---|
| Target Synonyms | GPHA2; GPA2; ZSIG51; Glycoprotein hormone alpha-2; Putative secreted protein Zsig51; Thyrostimulin subunit alpha | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 24-129 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96T91 |
|---|
Uniprot Id
Q96T91
Target Species
Human
Target Name
GPHA2
Target Full Name
Glycoprotein hormone alpha-2
Target Function
Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit alpha family
Target Tissue Specificity
Found in a variety of tissues.
Target Synonyms
GPHA2; GPA2; ZSIG51; Glycoprotein hormone alpha-2; Putative secreted protein Zsig51; Thyrostimulin subunit alpha
Target Background
GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).
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