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| Cat.No | ACP04326 | Target Name | GMPR2 |
|---|---|---|---|
| Target Synonyms | GMPR2GMP reductase 2; GMPR 2; EC 1.7.1.7; Guanosine 5'-monophosphate oxidoreductase 2; Guanosine monophosphate reductase 2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-366aa |
| Mol Weight | 55.8kDa | Protein Length | Full Length of Isoform 2 |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P2T1 |
|---|
Uniprot Id
Q9P2T1
Target Species
Human
Target Name
GMPR2
Target Full Name
GMP reductase 2
Target Function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation.
Target Protein Families
IMPDH/GMPR family, GuaC type 1 subfamily
Target Tissue Specificity
Highly expressed in heart, skeletal muscle, kidney, brain, liver, prostate, spleen, placenta, testis and ovary. Low expression in colon, thymus and peripheral blood leukocytes.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
GMPR2GMP reductase 2; GMPR 2; EC 1.7.1.7; Guanosine 5'-monophosphate oxidoreductase 2; Guanosine monophosphate reductase 2
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