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Discover the remarkable quality of our Recombinant Human GDF11, meticulously designed for optimal performance in neuroscience research. This product features the full length of mature Growth/differentiation factor 11 (GDF-11), a critical protein involved in the regulation of cellular growth and differentiation, particularly in the nervous system. Produced in E.coli, the Recombinant Human GDF11 covers an expression region of 299-407 amino acids and is equipped with an N-terminal 6xHis-SUMO tag to ensure efficient purification and detection. With a purity greater than 90% as determined by SDS-PAGE, our product is available in both liquid and lyophilized powder formats, catering to diverse research requirements. Choose the precision-crafted Recombinant Human GDF11 to elevate your neuroscience research with confidence and consistency.
Discover the remarkable quality of our Recombinant Human GDF11, meticulously designed for optimal performance in neuroscience research. This product features the full length of mature Growth/differentiation factor 11 (GDF-11), a critical protein involved in the regulation of cellular growth and differentiation, particularly in the nervous system.
Produced in E.coli, the Recombinant Human GDF11 covers an expression region of 299-407 amino acids and is equipped with an N-terminal 6xHis-SUMO tag to ensure efficient purification and detection. With a purity greater than 90% as determined by SDS-PAGE, our product is available in both liquid and lyophilized powder formats, catering to diverse research requirements. Choose the precision-crafted Recombinant Human GDF11 to elevate your neuroscience research with confidence and consistency.
| Cat.No | ACP02408 | Target Name | GDF11 |
|---|---|---|---|
| Target Synonyms | BMP 11; BMP-11; BMP11; Bone morphogenetic protein 11; GDF 11; GDF-11; Gdf11; GDF11_HUMAN; Growth differentiation factor 11; Growth/differentiation factor 11 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 299-407aa |
| Mol Weight | 28.5kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95390 |
|---|
Uniprot Id
O95390
Target Species
Human
Target Name
GDF11
Target Full Name
Growth/differentiation factor 11
Target Function
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family
Target Tissue Specificity
In the embryo, strong expression is seen in the palatal epithelia, including the medial edge epithelial and midline epithelial seam of the palatal shelves. Less pronounced expression is also seen throughout the palatal shelf and tongue mesenchyme.
Target Research Area
Neuroscience
Target Synonyms
BMP 11; BMP-11; BMP11; Bone morphogenetic protein 11; GDF 11; GDF-11; Gdf11; GDF11_HUMAN; Growth differentiation factor 11; Growth/differentiation factor 11
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