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| Cat.No | ACP00145 | Target Name | GRPEL1 |
|---|---|---|---|
| Target Synonyms | HMGE;Mt-GrpE#1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 28-217aa |
| Mol Weight | 48.2 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HAV7 |
|---|
Uniprot Id
Q9HAV7
Target Species
Human
Target Name
GRPEL1
Target Full Name
GrpE protein homolog 1, mitochondrial
Target Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
GrpE family
Target Research Area
Signal Transduction
Target Synonyms
FLJ25609; GREPEL 1; GREPEL1; GrpE like 1; GrpE like 1 mitochondrial; GrpE like protein cochaperone; GrpE protein homolog 1 mitochondrial; GrpE protein homolog 1; mitochondrial; GRPE1_HUMAN; GRPEL 1; Grpel1; HMGE; Mt GrpE#1; Mt-GrpE#1
Target Background
Enables identical protein binding activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial matrix and nucleoplasm.
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