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Recombinant Human GTP-binding protein GEM (GEM)

ACP22852

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22852 Target NameGEM
Target SynonymsGEM; KIRGTP-binding protein GEM; GTP-binding mitogen-induced T-cell protein; RAS-like protein KIRFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-296
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP55040
Background Information
  • Uniprot Id

    P55040

  • Target Species

    Human

  • Target Name

    GEM

  • Target Full Name

    GTP-binding protein GEM

  • Target Function

    Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Protein Families

    Small GTPase superfamily, RGK family

  • Target Tissue Specificity

    Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.

  • Target Synonyms

    GEM; KIRGTP-binding protein GEM; GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR

  • Target Background

    The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

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