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Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas (GNAS), Truncated

ACP17262

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Specifications

Cat.No	ACP17262	Target Name	GNAS
Target Synonyms	GNAS; GNAS1Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Adenylate cyclase-stimulating G alpha protein; Extra large alphas protein; XLalphas	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q5JWF2

Background Information

Uniprot Id

Q5JWF2
Target Species

Human
Target Name

GNAS
Target Full Name

Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
Target Function

Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms.
Target Involvement

GNAS hyperfunction (GNASHYP); ACTH-independent macronodular adrenal hyperplasia 1 (AIMAH1); Pseudohypoparathyroidism 1B (PHP1B); Pseudohypoparathyroidism 1C (PHP1C)
Target Subcellular Location

Cell membrane; Peripheral membrane protein. Apical cell membrane.
Target Protein Families

G-alpha family, G(s) subfamily
Target Synonyms

GNAS; GNAS1Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Adenylate cyclase-stimulating G alpha protein; Extra large alphas protein; XLalphas

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Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas (GNAS), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms XLas (GNAS), Truncated Now

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