Recombinant Human Guanine nucleotide-binding protein G (t) subunit alpha-2 (GNAT2)

Uniprot Id

P19087

Target Species

Human

Target Name

GNAT2

Target Full Name

Guanine nucleotide-binding protein G(t) subunit alpha-2

Target Function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

Target Involvement

Achromatopsia 4 (ACHM4)

Target Subcellular Location

Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.

Target Protein Families

G-alpha family, G(i/o/t/z) subfamily

Target Tissue Specificity

Retinal rod outer segment.

Target Synonyms

ACHM4; Cone type transducin alpha subunit; GNAT 2; GNAT C; Gnat2; GNAT2_HUMAN; GNATC; Guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 2; Guanine nucleotide binding protein G t subunit alpha 2; Guanine nucleotide-binding protein G(t) subunit alpha-2; Transducin alpha 2; Transducin alpha-2 chain; Transducin alpha2; Transducin cone specific alpha polypeptide

Target Background

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.