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| Cat.No | ACP23409 | Target Name | GUCA1A |
|---|---|---|---|
| Target Synonyms | GUCA1A; C6orf131; GCAP; GCAP1; GUCA1; Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-201 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P43080 |
|---|
Uniprot Id
P43080
Target Species
Human
Target Name
GUCA1A
Target Full Name
Guanylyl cyclase-activating protein 1
Target Function
Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.
Target Involvement
Cone dystrophy 3 (COD3)
Target Subcellular Location
Membrane; Lipid-anchor. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Target Tissue Specificity
In the retina, it is expressed in rod and cone photoreceptors.
Target Synonyms
GUCA1A; C6orf131; GCAP; GCAP1; GUCA1; Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A
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