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| Cat.No | ACP12263 | Target Name | HEATR1 |
|---|---|---|---|
| Target Synonyms | HEATR1; BAP28; UTP10HEAT repeat-containing protein 1; Protein BAP28; U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1; N-terminally processed] | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H583 |
|---|
Uniprot Id
Q9H583
Target Species
Human
Target Name
HEATR1
Target Full Name
HEAT repeat-containing protein 1
Target Function
Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
HEATR1/UTP10 family
Target Synonyms
HEATR1; BAP28; UTP10HEAT repeat-containing protein 1; Protein BAP28; U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1; N-terminally processed]
Target Background
Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in fibrillar center and mitochondrion. Implicated in pancreatic ductal carcinoma. Biomarker of glioblastoma.
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