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| Cat.No | ACP16178 | Target Name | SRCAP |
|---|---|---|---|
| Target Synonyms | SRCAP; KIAA0309; Helicase SRCAP; EC 3.6.4.-; Domino homolog 2; Snf2-related CBP activator | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZRS2 |
|---|
Uniprot Id
Q6ZRS2
Target Species
Human
Target Name
SRCAP
Target Full Name
Helicase SRCAP
Target Function
Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription.
Target Involvement
Floating-Harbor syndrome (FLHS)
Target Subcellular Location
Nucleus.
Target Protein Families
SNF2/RAD54 helicase family, SWR1 subfamily
Target Synonyms
SRCAP; KIAA0309; Helicase SRCAP; EC 3.6.4.-; Domino homolog 2; Snf2-related CBP activator
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