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| Cat.No | ACP01811 | Target Name | HBD |
|---|---|---|---|
| Target Synonyms | Delta-globin Hemoglobin delta chain | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 2-147aa |
| Mol Weight | 47.5 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P02042 |
|---|
Uniprot Id
P02042
Target Species
Human
Target Name
HBD
Target Full Name
Hemoglobin subunit delta
Target Function
Involved in oxygen transport from the lung to the various peripheral tissues.
Target Protein Families
Globin family
Target Tissue Specificity
Red blood cells.
Target Research Area
Transport
Target Synonyms
Delta-globin; HBD; HBD_HUMAN; Hemoglobin delta chain; Hemoglobin subunit delta
Target Background
The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.
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