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| Cat.No | ACP03234 | Target Name | HPS1 |
|---|---|---|---|
| Target Synonyms | Hermansky Pudlak syndrome 1 protein; Hermansky Pudlak syndrome gene; Hermansky Pudlak syndrome type 1; Hermansky-Pudlak syndrome 1; Hermansky-Pudlak syndrome 1 protein; HPS; HPS1; HPS1_HUMAN; MGC5277 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-324aa |
| Mol Weight | 63.5kDa | Protein Length | Full Length of Isoform III |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92902 |
|---|
Uniprot Id
Q92902
Target Species
Human
Target Name
HPS1
Target Full Name
BLOC-3 complex member HPS1
Target Function
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.
Target Involvement
Hermansky-Pudlak syndrome 1 (HPS1)
Target Tissue Specificity
Ubiquitous.
Target Research Area
Signal Transduction
Target Synonyms
Hermansky Pudlak syndrome 1 protein; Hermansky Pudlak syndrome gene; Hermansky Pudlak syndrome type 1; Hermansky-Pudlak syndrome 1; Hermansky-Pudlak syndrome 1 protein; HPS; HPS1; HPS1_HUMAN; MGC5277
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