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| Cat.No | ACP15247 | Target Name | HPS6 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-775 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86YV9 |
|---|
Uniprot Id
Q86YV9
Target Species
Human
Target Name
HPS6
Target Full Name
BLOC-2 complex member HPS6
Target Function
May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning.
Target Involvement
Hermansky-Pudlak syndrome 6 (HPS6)
Target Subcellular Location
Microsome membrane. Cytoplasm, cytosol. Early endosome membrane. Lysosome membrane.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
BLOC2S3; FLJ22501; Hermansky Pudlak syndrome 6 protein; Hermansky-Pudlak syndrome 6 protein; HPS6; HPS6 biogenesis of lysosomal organelles complex 2 subunit 3; HPS6_HUMAN; MGC20522; Ru; Ruby eye protein homolog; Ruby-eye protein homolog
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