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| Cat.No | ACP18154 | Target Name | PDE7A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-456 | Protein Length | full length of isoform PDE7A2 |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13946 |
|---|
Uniprot Id
Q13946
Target Species
Human
Target Name
PDE7A
Target Full Name
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A
Target Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
Target Subcellular Location
[Isoform PDE7A1]: Cytoplasm, cytosol. Note=PDE7A1 (57 kDa) is located mostly to soluble cellular fractions.; [Isoform PDE7A2]: Cytoplasm. Note=PDE7A2 (50 kDa) is located to particulate cellular fractions.
Target Protein Families
Cyclic nucleotide phosphodiesterase family, PDE7 subfamily
Target Tissue Specificity
PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
Target Synonyms
5''-cyclic phosphodiesterase 7A; HCP 1; HCP1; High affinity cAMP specific 3'5' cyclic phosphodiesterase 7A; High affinity cAMP-specific 3''; P2A; PDE 7; PDE 7A; PDE1/PDE2 yeast human complement of; PDE7; PDE71; PDE7A; PDE7A_HUMAN; Phosphodiesterase 7A; Phosphodiesterase isozyme 7; Phosphodiesterase7A; Rolipram insensitive phosphodiesterase type 7 ; TM 22; TM22
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