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| Cat.No | ACP12678 | Target Name | KAT6A |
|---|---|---|---|
| Target Synonyms | HAT 3; Histone acetyltransferase MYST3; Monocytic leukemia zinc finger protein; MOZ; MOZ, YBF2/SAS3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92794 |
|---|
Uniprot Id
Q92794
Target Species
Human
Target Name
KAT6A
Target Full Name
Histone acetyltransferase KAT6A
Target Function
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
Target Involvement
Mental retardation, autosomal dominant 32 (MRD32)
Target Subcellular Location
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Note=Recruited into PML body after DNA damage.
Target Protein Families
MYST (SAS/MOZ) family
Target Synonyms
HAT 3; Histone acetyltransferase MYST3; Monocytic leukemia zinc finger protein; MOZ; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; MYST protein 3; MYST-3; MYST3; MYST3_HUMAN; OTTHUMP00000197392; OTTHUMP00000197394; OTTHUMP00000225722; Runt related transcription factor binding protein 2; Runt-related transcription factor-binding protein 2; RUNXBP2 ; SAS2 ; SAS2 and TIP60 protein 3; TIP60 protein 3; YBF2/SAS3; ZC2HC6A; Zinc finger protein 220; ZNF220
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