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| Cat.No | ACP16364 | Target Name | H3F3C |
|---|---|---|---|
| Target Synonyms | family 3C; H3.5; H3C_HUMAN; h3f3c; Histone H3.3C; Histone H3.5; Histone variant H3.5, H3 histone | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-135 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6NXT2 |
|---|
Uniprot Id
Q6NXT2
Target Species
Human
Target Name
H3-5
Target Full Name
Histone H3.3C
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H3 family
Target Tissue Specificity
Specifically expressed in the seminiferous tubules of testis.
Target Synonyms
H3 histone, family 3C; H3.5; H3C_HUMAN; h3f3c; Histone H3.3C; Histone H3.5; Histone variant H3.5
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