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| Cat.No | ACP17699 | Target Name | HAGH |
|---|---|---|---|
| Target Synonyms | HAGH; GLO2; HAGH1Hydroxyacylglutathione hydrolase; mitochondrial; EC 3.1.2.6; Glyoxalase II; Glx II | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 14-308 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16775 |
|---|
Uniprot Id
Q16775
Target Species
Human
Target Name
HAGH
Target Full Name
Hydroxyacylglutathione hydrolase, mitochondrial
Target Function
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Target Subcellular Location
[Isoform 1]: Mitochondrion matrix.; [Isoform 2]: Cytoplasm.
Target Protein Families
Metallo-beta-lactamase superfamily, Glyoxalase II family
Target Tissue Specificity
Expressed in liver and kidney.
Target Research Area
Metabolism
Target Synonyms
HAGH; GLO2; HAGH1Hydroxyacylglutathione hydrolase; mitochondrial; EC 3.1.2.6; Glyoxalase II; Glx II
Target Background
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene.
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