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| Cat.No | ACP10267 | Target Name | IGSF5 |
|---|---|---|---|
| Target Synonyms | IGSF5; JAM4; Immunoglobulin superfamily member 5; IgSF5; Junctional adhesion molecule 4; JAM-4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NSI5 |
|---|
Uniprot Id
Q9NSI5
Target Species
Human
Target Name
IGSF5
Target Full Name
Immunoglobulin superfamily member 5
Target Function
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
Target Subcellular Location
Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction.
Target Protein Families
Immunoglobulin superfamily
Target Synonyms
IGSF5; JAM4; Immunoglobulin superfamily member 5; IgSF5; Junctional adhesion molecule 4; JAM-4
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