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Recombinant Human Inorganic pyrophosphatase 2, mitochondrial (PPA2)

ACP11836

Number
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Specifications


Cat.No ACP11836 Target NamePPA2
Target SynonymsHSPC124; Inorganic pyrophosphatase 2; Inorganic pyrophosphatase 2, mitochondrial; IPYR2_HUMAN; mitochondrial; Ppa2; PPase 2; PPase2; Pyrophosphatase (inorganic) 2; Pyrophosphatase SID6 306 ; Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; SID6 306FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range33-334
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9H2U2
Background Information
  • Uniprot Id

    Q9H2U2

  • Target Species

    Human

  • Target Name

    PPA2

  • Target Full Name

    Inorganic pyrophosphatase 2, mitochondrial

  • Target Function

    Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function.

  • Target Involvement

    Sudden cardiac failure, alcohol-induced (SCFAI); Sudden cardiac failure, infantile (SCFI)

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    PPase family

  • Target Tissue Specificity

    Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.

  • Target Synonyms

    HSPC124; Inorganic pyrophosphatase 2; Inorganic pyrophosphatase 2, mitochondrial; IPYR2_HUMAN; mitochondrial; Ppa2; PPase 2; PPase2; Pyrophosphatase (inorganic) 2; Pyrophosphatase SID6 306 ; Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; SID6 306

  • Target Background

    The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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