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| Cat.No | ACP11712 | Target Name | IMPAD1 |
|---|---|---|---|
| Target Synonyms | IMPAD1; IMPA3; Golgi-resident adenosine 3' | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NX62 |
|---|
Uniprot Id
Q9NX62
Target Species
Human
Target Name
BPNT2
Target Full Name
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase
Target Function
Exhibits 3'-nucleotidase activity toward adenosine 3',5'-bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, I(1,3,4)P3, I(1,4,5)P3 and I(1,3,4,5)P4.
Target Involvement
Chondrodysplasia with joint dislocations, GPAPP type (CDP-GPAPP)
Target Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein.
Target Protein Families
Inositol monophosphatase superfamily
Target Synonyms
IMPAD1; IMPA3; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Golgi-resident PAP phosphatase; gPAPP; EC 3.1.3.7; Inositol monophosphatase domain-containing protein 1; Myo-inositol monophosphatase A3; Phosphoadenosine phosphate 3'-nucleotidase
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