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| Cat.No | ACP01953 | Target Name | IGFBP5 |
|---|---|---|---|
| Target Synonyms | IBP-5;IGF-binding protein 5;IGFBP-5 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 21-272aa |
| Mol Weight | 36.0 kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P24593 |
|---|
Uniprot Id
P24593
Target Species
Human
Target Name
IGFBP5
Target Full Name
Insulin-like growth factor-binding protein 5
Target Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Osteosarcoma, and at lower levels in liver, kidney and brain.
Target Research Area
Signal Transduction
Target Synonyms
IBP 5; IBP-5; IBP5; IBP5_HUMAN; IGF binding protein 5; IGF BP5; IGF-binding protein 5; IGFBP 5; IGFBP-5; IGFBP5; Insulin like growth factor binding protein 5; Insulin-like growth factor-binding protein 5
Target Background
Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of smooth muscle cell proliferation. Part of insulin-like growth factor ternary complex. Biomarker of pulmonary fibrosis.
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