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| Cat.No | ACP19418 | Target Name | INTS12 |
|---|---|---|---|
| Target Synonyms | INTS12; PHF22; SBBI22; Integrator complex subunit 12; Int12; PHD finger protein 22 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-462 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96CB8 |
|---|
Uniprot Id
Q96CB8
Target Species
Human
Target Name
INTS12
Target Full Name
Integrator complex subunit 12
Target Function
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Target Subcellular Location
Nucleus.
Target Protein Families
Integrator subunit 12 family
Target Synonyms
INTS12; PHF22; SBBI22; Integrator complex subunit 12; Int12; PHD finger protein 22
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