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| Cat.No | ACP10012 | Target Name | ITGA11 |
|---|---|---|---|
| Target Synonyms | integrin a11; Integrin alpha 11; Integrin alpha-11; ITA11_HUMAN; ITGA11 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UKX5 |
|---|
Uniprot Id
Q9UKX5
Target Species
Human
Target Name
ITGA11
Target Full Name
Integrin alpha-11
Target Function
Integrin alpha-11/beta-1 is a receptor for collagen.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Integrin alpha chain family
Target Tissue Specificity
According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small i
Target Synonyms
integrin a11; Integrin alpha 11; Integrin alpha-11; ITA11_HUMAN; ITGA11
Target Background
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.
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