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The region for expressing recombinant Human IFNA4 contains amino acids 24-189. The expected molecular weight for the IFNA4 protein is calculated to be 35.4 kDa. This IFNA4 protein is produced using e.coli expression system. The IFNA4 gene fragment has been modified by fusing the N-terminal 6xHis-SUMO tag, providing convenience in detecting and purifying the recombinant IFNA4 protein during the following stages.Human interferon alpha-4 (IFNA4) is a member of the interferon-alpha family, a group of cytokines that play a crucial role in the antiviral immune response. IFNA4 is produced by various immune cells, particularly leukocytes, in response to viral infections. Its main function is to inhibit viral replication and spread by inducing the expression of antiviral proteins within infected cells. Additionally, IFNA4 contributes to the activation of immune cells, enhancing the overall antiviral defense. Research on IFNA4 spans virology, immunology, and clinical medicine, exploring its potential therapeutic applications in treating viral infections, certain cancers, and autoimmune diseases.
The region for expressing recombinant Human IFNA4 contains amino acids 24-189. The expected molecular weight for the IFNA4 protein is calculated to be 35.4 kDa. This IFNA4 protein is produced using e.coli expression system. The IFNA4 gene fragment has been modified by fusing the N-terminal 6xHis-SUMO tag, providing convenience in detecting and purifying the recombinant IFNA4 protein during the following stages.Human interferon alpha-4 (IFNA4) is a member of the interferon-alpha family, a group of cytokines that play a crucial role in the antiviral immune response. IFNA4 is produced by various immune cells, particularly leukocytes, in response to viral infections. Its main function is to inhibit viral replication and spread by inducing the expression of antiviral proteins within infected cells. Additionally, IFNA4 contributes to the activation of immune cells, enhancing the overall antiviral defense. Research on IFNA4 spans virology, immunology, and clinical medicine, exploring its potential therapeutic applications in treating viral infections, certain cancers, and autoimmune diseases.
| Cat.No | ACP04410 | Target Name | IFNA4 |
|---|---|---|---|
| Target Synonyms | IFNA4Interferon alpha-4; IFN-alpha-4; Interferon alpha-4B; Interferon alpha-76; Interferon alpha-M1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 24-189aa |
| Mol Weight | 35.4kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P05014 |
|---|
Uniprot Id
P05014
Target Species
Human
Target Name
IFNA4
Target Full Name
Interferon alpha-4
Target Function
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Target Subcellular Location
Secreted.
Target Protein Families
Alpha/beta interferon family
Target Research Area
Cancer
Target Synonyms
IFNA4Interferon alpha-4; IFN-alpha-4; Interferon alpha-4B; Interferon alpha-76; Interferon alpha-M1
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