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| Cat.No | ACP10367 | Target Name | IRF2BPL |
|---|---|---|---|
| Target Synonyms | IRF2BPL; C14orf4; EAP1; KIAA1865; My039; Probable E3 ubiquitin-protein ligase IRF2BPL; EC 2.3.2.27; Enhanced at puberty protein 1; Interferon regulatory factor 2-binding protein-like | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-796 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H1B7 |
|---|
Uniprot Id
Q9H1B7
Target Species
Human
Target Name
IRF2BPL
Target Full Name
Probable E3 ubiquitin-protein ligase IRF2BPL
Target Function
Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (Probable). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.
Target Subcellular Location
Nucleus.
Target Protein Families
IRF2BP family
Target Tissue Specificity
Highly expressed in the heart, moderately in skeletal muscle and pancreas, and weakly in brain, kidney, liver, testis, thyroid gland and lymphocytes.
Target Synonyms
IRF2BPL; C14orf4; EAP1; KIAA1865; My039; Probable E3 ubiquitin-protein ligase IRF2BPL; EC 2.3.2.27; Enhanced at puberty protein 1; Interferon regulatory factor 2-binding protein-like
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