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Recombinant Human Interleukin-10 receptor subunit beta (IL10RB), Truncated

ACP18610

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Specifications

Cat.No	ACP18610	Target Name	IL10RB
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q08334

Background Information

Uniprot Id

Q08334
Target Species

Human
Target Name

IL10RB
Target Full Name

Interleukin-10 receptor subunit beta
Target Function

Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
Target Involvement

Inflammatory bowel disease 25 (IBD25)
Target Subcellular Location

Membrane; Single-pass type I membrane protein.
Target Protein Families

Type II cytokine receptor family
Target Synonyms

Cd210 ; CDw210b; CRF2 4; CRF2-4; CRFB4; Cytokine receptor class II ; Cytokine receptor class II CRF2 4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; Cytokine receptor family II member 4 ; D21S58; D21S66; I10R2_HUMAN; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; IL10R2; IL10RB; Interleukin 10 receptor beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta

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Recombinant Human Interleukin-10 receptor subunit beta (IL10RB), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Interleukin-10 receptor subunit beta (IL10RB), Truncated Now

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