Recombinant Human Interleukin-20 receptor subunit alpha (IL20RA), Truncated

Uniprot Id

Q9UHF4

Target Species

Human

Target Name

IL20RA

Target Full Name

Interleukin-20 receptor subunit alpha

Target Function

The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.

Target Subcellular Location

Membrane; Single-pass type I membrane protein.

Target Protein Families

Type II cytokine receptor family

Target Tissue Specificity

Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.

Target Synonyms

class II cytokine receptor ZCYTOR7; CRF2 8; CRF2-8; Cytokine receptor class II member 8; Cytokine receptor class-II member 8; Cytokine receptor family 2 member 8; I20RA_HUMAN; IL 20R alpha; IL 20R1; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20R1; IL-20RA; IL20 Receptor alpha; IL20RA; Interleukin 20 receptor alpha chain; Interleukin 20 receptor, alpha; interleukin-20 receptor I; Interleukin-20 receptor subunit alpha; ZcytoR7

Target Background

This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants.