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Recombinant Human Inverted formin-2 (INF2), Truncated

ACP17679

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Specifications

Cat.No	ACP17679	Target Name	INF2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q27J81

Background Information

Uniprot Id

Q27J81
Target Species

Human
Target Name

INF2
Target Full Name

Inverted formin-2
Target Function

Severs actin filaments and accelerates their polymerization and depolymerization.
Target Involvement

Focal segmental glomerulosclerosis 5 (FSGS5); Charcot-Marie-Tooth disease, dominant, intermediate type, E (CMTDIE)
Target Subcellular Location

Cytoplasm, perinuclear region.
Target Protein Families

Formin homology family
Target Tissue Specificity

Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Target Synonyms

C14orf151; C14orf173; CMTDIE; DKFZp762A0214; FLJ22056; FSGS5; HBEAG binding protein 2 binding protein C; HBEBP2 binding protein C; HBEBP2-binding protein C; INF 2; inf2; INF2_HUMAN; Inverted formin 2; Inverted formin FH2 and WH2 domain containing; Inverted formin-2; MGC13251; pp9484
Target Background

This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

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Recombinant Human Inverted formin-2 (INF2), Truncated

Specifications

Immunogen Information

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