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| Cat.No | ACP06291 | Target Name | KCNJ18 |
|---|---|---|---|
| Target Synonyms | KCNJ18; Inward rectifier potassium channel 18; Inward rectifier K(+) channel Kir2.6; Potassium channel; inwardly rectifying subfamily J member 18 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | B7U540 |
|---|
Uniprot Id
B7U540
Target Species
Human
Target Name
KCNJ18
Target Full Name
Inward rectifier potassium channel 18
Target Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Target Involvement
Thyrotoxic periodic paralysis 2 (TTPP2)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Inward rectifier-type potassium channel (TC 1.A.2.1) family, KCNJ12 subfamily
Target Tissue Specificity
Specifically expressed in skeletal muscle.
Target Synonyms
KCNJ18; Inward rectifier potassium channel 18; Inward rectifier K(+) channel Kir2.6; Potassium channel; inwardly rectifying subfamily J member 18
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