Recombinant Human Islet amyloid polypeptide (IAPP), Truncated

ACP04830

Number

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Specifications

Cat.No	ACP04830	Target Name	IAPP
Target Synonyms	Amylin; DAP; Diabetes associated peptide; Diabetes-associated peptide; IAP; IAPP; IAPP_HUMAN; Insulinoma amyloid peptide; Islet amyloid polypeptide (diabetes associated peptide, amylin); Islet amyloid polypeptide	Form	Liquid or Lyophilized powder
Expression System	Yeast	Expression Range	34-70aa
Mol Weight	5.9 kDa	Protein Length	Partial
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P10997

Background Information

Uniprot Id

P10997
Target Species

Human
Target Name

IAPP
Target Full Name

Islet amyloid polypeptide
Target Function

Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Target Subcellular Location

Secreted.
Target Protein Families

Calcitonin family
Target Research Area

Signal Transduction
Target Synonyms

Amylin; DAP; Diabetes associated peptide; Diabetes-associated peptide; IAP; IAPP; IAPP_HUMAN; Insulinoma amyloid peptide; Islet amyloid polypeptide (diabetes associated peptide, amylin); Islet amyloid polypeptide
Target Background

This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.

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Recombinant Human Islet amyloid polypeptide (IAPP), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Islet amyloid polypeptide (IAPP), Truncated Now

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