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| Cat.No | ACP14177 | Target Name | JPH3 |
|---|---|---|---|
| Target Synonyms | JP-3; JP3; JPH3; JPH3_HUMAN; Junctophilin 3; Junctophilin type 3; Junctophilin-3; TNRC22; Trinucleotide repeat-containing gene 22 protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WXH2 |
|---|
Uniprot Id
Q8WXH2
Target Species
Human
Target Name
JPH3
Target Full Name
Junctophilin-3
Target Function
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory.
Target Involvement
Huntington disease-like 2 (HDL2)
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Target Protein Families
Junctophilin family
Target Tissue Specificity
Specifically expressed in brain.
Target Synonyms
JP-3; JP3; JPH3; JPH3_HUMAN; Junctophilin 3; Junctophilin type 3; Junctophilin-3; TNRC22; Trinucleotide repeat-containing gene 22 protein
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